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This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

Genetics --- Human genetics --- medische genetica --- genetica

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This essential should serve as an introduction for a contemporary public discussion on genetic engineering. Genetic engineering affects us all in many areas and we must dare to think more colorful and further. In fact, the complete genetic material of viruses and bacteria can already be chemically produced and "brought to life". With genetic surgery, medicine is at a crossroad do we want to treat hereditary diseases or "repair" them genetically? And the analysis of the genetic material of thousands of people reveals information that is related to complex diseases, but also to characteristics such as intelligence. How should we use this knowledge? The question is hardly whether we want genetic engineering, but rather how we use it. This Springer essential is a translation of the original German 1st edition essentials, Gentechnik by Röbbe Wünschiers, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2019. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors. The content How is the genetic material read and what does the information say? Which methods can be used to modify the genetic material and what are the goals? Who owns genetic information and what can be marketed and how? How does the environment affect the genetic material? Do we want a liberalization of genetic engineering as a civil science? The target groups All those who would like to inform themselves about genetic engineering even without previous knowledge. The Author Röbbe Wünschiers holds a doctorate in plant physiology and a habilitation in genetics. He researches and teaches as professor of biochemistry and molecular biology at the University of Applied Sciences Mittweida/Germany.

Genetics --- Zoology --- Human genetics --- Biotechnology --- medische genetica --- genetica --- biotechnologie --- zoölogie

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Genetics --- Molecular biology --- genetica --- moleculaire biologie

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Biomathematics. Biometry. Biostatistics --- Genetics --- bio-informatica --- genetica

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Human genetics --- Ophthalmology --- medische genetica --- oftalmologie